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| Career Singles Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Singles | PA | Years | Single Season Leaderboard |
| 1. | Anthony Gwynn | 1767 | 7637 | 2007-2021 | |
| 2. | Alejandro Machado | 1749 | 7843 | 2007-2019 | |
| 3. | Grady Sizemore | 1648 | 8463 | 2007-2020 | |
| 4. | Richard Sheldon | 1573 | 9146 | 2007-2021 | |
| 5. | Chris Lubanski | 1566 | 7595 | 2010-2021 | |
| 6. | Robert Cervantes | 1564 | 7154 | 2010-2021 | |
| 7. | Albert Pujols * | 1502 | 7874 | 2007-2018 | |
| 8. | Dallas McPherson | 1485 | 7677 | 2007-2019 | |
| 9. | Tony Miller | 1477 | 8041 | 2007-2019 | |
| 10. | Paul Haruki | 1463 | 9098 | 2007-2021 | |
| 11. | Josh Wilson | 1453 | 6687 | 2007-2017 | |
| 12. | William Lamberth | 1432 | 9230 | 2007-2021 | |
| 13. | Felix Veach | 1428 | 6274 | 2009-2021 | |
| 14. | Ferdin Tejada | 1421 | 5972 | 2010-2020 | |
| 15. | Omar Infante | 1415 | 6921 | 2007-2020 | |
| 16. | Yoshitomo Tani | 1367 | 6844 | 2007-2017 | |
| 17. | Jeremy Brown | 1350 | 6640 | 2007-2019 | |
| 18. | Brian Specht | 1345 | 7917 | 2007-2019 | |
| 19. | Robinson Cano | 1339 | 6631 | 2008-2020 | |
| 20. | Casimiro Diaz | 1336 | 7919 | 2007-2021 | |
| 21. | Keith Pollock | 1333 | 6716 | 2010-2021 | |
| 22. | Johnny Miller | 1331 | 8765 | 2008-2021 | |
| 23. | Matt Macri | 1329 | 7607 | 2007-2020 | |
| 24. | Manuel Melo | 1323 | 6800 | 2007-2018 | |
| 25. | Rueben Manzo | 1304 | 7705 | 2010-2021 | |
| 26. | Michael Woods | 1294 | 7617 | 2007-2018 | |
| 27. | Matt Murton | 1282 | 6951 | 2007-2017 | |
| 28. | Shin-Soo Choo | 1273 | 6849 | 2007-2017 | |
| 29. | Ardley Jansen | 1248 | 6216 | 2007-2017 | |
| 30. | Renato Fajardo | 1236 | 6241 | 2010-2021 | |
| 31. | Jarrod Saltalamacchia | 1222 | 5970 | 2008-2019 | |
| 32. | Hollis Defazio | 1209 | 7732 | 2010-2021 | |
| Danny Garcia | 1209 | 5924 | 2008-2018 | ||
| 34. | Justin Knoedler | 1205 | 6607 | 2007-2018 | |
| 35. | Tony Torcato | 1202 | 5548 | 2007-2016 | |
| 36. | Wilson Betemit | 1197 | 8055 | 2007-2020 | |
| 37. | Matt Moses | 1191 | 6020 | 2010-2020 | |
| 38. | Adam Donachie | 1187 | 6403 | 2009-2021 | |
| 39. | Mickey Hall | 1159 | 6505 | 2010-2020 | |
| 40. | Lance Niekro | 1155 | 5775 | 2008-2020 | |
| 41. | Carl Crawford | 1150 | 5941 | 2007-2018 | |
| 42. | Jeremy Hermida | 1146 | 6069 | 2007-2018 | |
| 43. | Juan Gonzalez | 1138 | 6134 | 2009-2020 | |
| 44. | Nick Swisher | 1131 | 7853 | 2007-2018 | |
| 45. | Michael Rogers | 1124 | 6089 | 2009-2021 | |
| 46. | Justin Brashear | 1122 | 5783 | 2009-2020 | |
| 47. | Freddie Bynum | 1121 | 6456 | 2007-2018 | |
| 48. | Chris Snelling | 1118 | 8106 | 2007-2020 | |
| 49. | Adan Guerra | 1105 | 5929 | 2012-2021 | |
| Toshiya Nakashima | 1105 | 6600 | 2007-2019 | ||
| 51. | Kyle Walker | 1096 | 6394 | 2010-2021 | |
| 52. | Angel Pagan | 1089 | 4955 | 2007-2018 | |
| 53. | Bradley Small | 1087 | 6338 | 2011-2021 | |
| 54. | Irwin Centeno | 1080 | 5411 | 2007-2017 | |
| 55. | Frank Kirkman | 1074 | 6292 | 2012-2021 | |
| Carlos Quentin | 1074 | 6771 | 2010-2020 | ||
| 57. | Rickie Weeks | 1073 | 7443 | 2007-2018 | |
| 58. | Everett Stadler | 1069 | 4969 | 2014-2021 | |
| Jeremy Reed | 1069 | 6109 | 2007-2017 | ||
| 60. | Scott White | 1068 | 5114 | 2009-2020 | |
| 61. | Gabriel Crow | 1065 | 5878 | 2010-2021 | |
| 62. | Luis Rivas | 1064 | 5461 | 2007-2016 | |
| 63. | Leopoldo Arguello | 1056 | 5139 | 2013-2021 | |
| 64. | Angel Molina | 1049 | 6236 | 2007-2018 | |
| 65. | Tony Richie | 1048 | 4925 | 2007-2017 | |
| 66. | Chad Tracy | 1047 | 4931 | 2007-2015 | |
| 67. | William Bergolla | 1039 | 5332 | 2007-2019 | |
| 68. | Michael Moon | 1037 | 5086 | 2008-2019 | |
| 69. | Juan Hernandez | 1029 | 5574 | 2012-2021 | |
| 70. | Franky Espada | 1025 | 5343 | 2012-2021 | |
| 71. | Choo Freeman | 1022 | 5222 | 2007-2015 | |
| 72. | Ray Sadler | 1021 | 5721 | 2007-2017 | |
| 73. | Barney Cobas | 1020 | 5175 | 2012-2021 | |
| Shawn Garrett | 1020 | 6183 | 2007-2016 | ||
| 75. | Carlo Barrera | 1017 | 8139 | 2007-2020 | |
| 76. | Michael Garciaparra | 1016 | 6736 | 2009-2020 | |
| 77. | Blair Thomson | 1014 | 5498 | 2011-2021 | |
| 78. | Noochie Varner | 1005 | 5692 | 2007-2016 | |
| 79. | Johnnie Harley | 1004 | 6619 | 2011-2021 | |
| C.J. Bressoud | 1004 | 5222 | 2011-2021 | ||
| Cristian Guerrero | 1004 | 5141 | 2007-2016 | ||
| 82. | Mark Teixeira | 1001 | 7286 | 2007-2019 | |
| 83. | Aaron Braza | 1000 | 7218 | 2007-2018 | |
| 84. | Damian James | 999 | 6909 | 2010-2021 | |
| 85. | Mike Spidale | 994 | 6279 | 2007-2018 | |
| 86. | Dylan Lammond | 992 | 5402 | 2013-2021 | |
| 87. | Brennan Boesch | 991 | 5405 | 2011-2021 | |
| Andrew Heller | 991 | 5177 | 2012-2021 | ||
| 89. | Samuel Gladstone | 989 | 5598 | 2011-2021 | |
| 90. | Lee Mitchell | 984 | 5231 | 2008-2018 | |
| 91. | Travis Ishikawa | 982 | 5795 | 2009-2020 | |
| 92. | Earl Allison | 978 | 4998 | 2007-2017 | |
| 93. | Corey Patterson | 975 | 5698 | 2007-2017 | |
| 94. | Prince Gilbreath | 971 | 7145 | 2008-2021 | |
| 95. | Mario Barbeau | 970 | 5597 | 2012-2021 | |
| John Russell | 970 | 4992 | 2012-2021 | ||
| Tim Moss | 970 | 5296 | 2007-2018 | ||
| Dominic Rich | 970 | 4506 | 2007-2014 | ||
| 99. | Michael Doyle | 967 | 7123 | 2009-2021 | |
| 100. | John Baker | 966 | 5251 | 2007-2018 |
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