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| Career OPS Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | OPS | PA | Years | Single Season Leaderboard |
| 1. | Lance Berkman * | .9861 | 5621 | 2007-2016 | |
| 2. | Steven Maccaskill | .9762 | 5201 | 2013-2021 | |
| 3. | Tom Chisholm | .9340 | 3945 | 2016-2021 | |
| 4. | Johnny Miller | .9245 | 8765 | 2008-2021 | |
| 5. | Michael Garciaparra | .9193 | 6736 | 2009-2020 | |
| 6. | Carlo Barrera | .9144 | 8139 | 2007-2020 | |
| 7. | Carlos Pena | .9070 | 5963 | 2007-2016 | |
| 8. | Mark Teixeira | .9041 | 7286 | 2007-2019 | |
| 9. | Scott Hairston | .9023 | 6377 | 2007-2017 | |
| 10. | Robert Cervantes | .9012 | 7154 | 2010-2021 | |
| 11. | Christopher Rode | .9008 | 5035 | 2014-2021 | |
| 12. | Florentino Pina | .8934 | 4164 | 2014-2021 | |
| 13. | Darwin Alexander | .8874 | 6534 | 2007-2018 | |
| 14. | Albert Pujols * | .8870 | 7874 | 2007-2018 | |
| 15. | Paul Haruki | .8853 | 9098 | 2007-2021 | |
| 16. | Alex Rodriguez * | .8826 | 3419 | 2007-2012 | |
| 17. | Travis Hafner | .8787 | 4941 | 2007-2015 | |
| 18. | Kyle Walker | .8677 | 6394 | 2010-2021 | |
| 19. | Justin Morneau | .8632 | 6551 | 2007-2016 | |
| 20. | Fernando Gonzalez | .8631 | 4813 | 2013-2021 | |
| 21. | Eric Chavez | .8627 | 4673 | 2007-2016 | |
| 22. | Rueben Manzo | .8621 | 7705 | 2010-2021 | |
| 23. | Freeman Pace | .8613 | 3288 | 2017-2021 | |
| 24. | Juan Hernandez | .8596 | 5574 | 2012-2021 | |
| 25. | Nick Swisher | .8586 | 7853 | 2007-2018 | |
| 26. | Chris Duncan | .8582 | 5233 | 2007-2016 | |
| 27. | Alfonso Romero | .8537 | 3010 | 2017-2021 | |
| 28. | Leonardo Cepeda | .8535 | 4877 | 2013-2021 | |
| 29. | Joel Echague | .8519 | 4835 | 2014-2021 | |
| 30. | William Lamberth | .8501 | 9230 | 2007-2021 | |
| 31. | Ivan Lawhon | .8491 | 6750 | 2007-2018 | |
| 32. | Connor Maccause | .8483 | 5161 | 2013-2021 | |
| 33. | Brad Wilkerson | .8482 | 4682 | 2007-2014 | |
| 34. | Manuel Leon | .8450 | 3792 | 2015-2021 | |
| 35. | Jorge Cortes | .8449 | 5244 | 2008-2016 | |
| 36. | Richard Sheldon | .8424 | 9146 | 2007-2021 | |
| 37. | Victor Martinez | .8410 | 4115 | 2007-2015 | |
| 38. | Chris Snelling | .8405 | 8106 | 2007-2020 | |
| 39. | Tony Miller | .8383 | 8041 | 2007-2019 | |
| 40. | Austin Kearns | .8373 | 5218 | 2007-2016 | |
| 41. | Josh Phelps | .8351 | 3896 | 2007-2013 | |
| 42. | Troy Glaus | .8330 | 4218 | 2007-2014 | |
| 43. | Carlos Beltran | .8311 | 6443 | 2007-2016 | |
| 44. | Johnnie Harley | .8303 | 6619 | 2011-2021 | |
| 45. | Dylan Lammond | .8300 | 5402 | 2013-2021 | |
| 46. | Joel Perez | .8299 | 3019 | 2017-2021 | |
| 47. | Brandon Phillips | .8291 | 6332 | 2007-2018 | |
| 48. | Mike O'Keefe | .8283 | 5813 | 2007-2017 | |
| 49. | Chris Lubanski | .8276 | 7595 | 2010-2021 | |
| 50. | Michael Peck | .8271 | 4023 | 2014-2021 | |
| 51. | Eric Byrnes | .8270 | 4237 | 2007-2014 | |
| 52. | Johnnie Gardner | .8257 | 3319 | 2017-2021 | |
| 53. | Bradley Small | .8241 | 6338 | 2011-2021 | |
| 54. | Eric Hinske | .8238 | 3448 | 2007-2013 | |
| 55. | Michael Clark | .8237 | 5716 | 2012-2021 | |
| 56. | Michael Rogers | .8233 | 6089 | 2009-2021 | |
| 57. | Matt Cepicky | .8228 | 3448 | 2007-2012 | |
| 58. | Preston Wilson | .8222 | 4762 | 2007-2014 | |
| 59. | Adam Dunn | .8210 | 4396 | 2007-2015 | |
| 60. | Angel Molina | .8199 | 6236 | 2007-2018 | |
| 61. | Jason Dubois | .8188 | 4057 | 2007-2013 | |
| 62. | Tony Acevedo | .8186 | 3196 | 2007-2015 | |
| 63. | Jeremy Brown | .8184 | 6640 | 2007-2019 | |
| 64. | Harold Gervais | .8184 | 5463 | 2012-2020 | |
| 65. | Miguel Tejada | .8181 | 3653 | 2007-2012 | |
| 66. | Kevin Mench | .8173 | 4422 | 2007-2014 | |
| 67. | Jose Perez | .8173 | 4586 | 2014-2021 | |
| 68. | Jesus Gonzalez | .8166 | 4591 | 2014-2021 | |
| 69. | Daniel Kessler | .8138 | 5989 | 2010-2021 | |
| 70. | Dernell Stenson | .8136 | 4141 | 2008-2015 | |
| 71. | Aaron Braza | .8130 | 7218 | 2007-2018 | |
| 72. | Justin Knoedler | .8128 | 6607 | 2007-2018 | |
| 73. | Connor Macgrime | .8128 | 4849 | 2014-2021 | |
| 74. | Robert Tabron | .8127 | 4835 | 2011-2020 | |
| 75. | Mike Spidale | .8127 | 6279 | 2007-2018 | |
| 76. | Mike Rouse | .8115 | 4375 | 2007-2014 | |
| 77. | Ryan Howard | .8109 | 4349 | 2007-2015 | |
| 78. | Chipper Jones * | .8109 | 3252 | 2007-2012 | |
| 79. | Hank Blalock | .8096 | 5944 | 2007-2017 | |
| 80. | Mickey Hall | .8096 | 6505 | 2010-2020 | |
| 81. | Paul McAnulty | .8093 | 6239 | 2007-2017 | |
| 82. | Chad Tracy | .8093 | 4931 | 2007-2015 | |
| 83. | Juan Mariscal | .8084 | 4188 | 2014-2021 | |
| 84. | Lukasz Starszewski | .8083 | 3749 | 2016-2021 | |
| 85. | Matt Macri | .8082 | 7607 | 2007-2020 | |
| 86. | Laynce Nix | .8081 | 5614 | 2007-2017 | |
| 87. | Lee Mitchell | .8080 | 5231 | 2008-2018 | |
| 88. | Hollis Defazio | .8078 | 7732 | 2010-2021 | |
| 89. | Josh Wilson | .8075 | 6687 | 2007-2017 | |
| 90. | Juan Uribe | .8072 | 3364 | 2007-2012 | |
| 91. | Michael Ryan | .8069 | 4400 | 2007-2014 | |
| 92. | Christopher Shoulders | .8052 | 3287 | 2017-2021 | |
| 93. | C.J. Bressoud | .8051 | 5222 | 2011-2021 | |
| 94. | Adolf Bermont | .8047 | 3755 | 2016-2021 | |
| 95. | Nathan Haynes | .8011 | 4354 | 2009-2016 | |
| 96. | Nick Green | .8005 | 3844 | 2007-2012 | |
| 97. | Geronimo Rosales | .7993 | 6747 | 2010-2021 | |
| 98. | Henning Inken | .7987 | 4327 | 2014-2020 | |
| 99. | Bill Kolar | .7987 | 5746 | 2007-2016 | |
| 100. | Jason Bay | .7966 | 4372 | 2007-2014 |
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