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| Single-Season Games Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Games | PA | Year | Career Leaderboard |
| 1. | Troy Glaus | 163 | 668 | 2012 | |
| 2. | Antonio Sandoval | 162 | 686 | 2021 | |
| David Coyer | 162 | 642 | 2021 | ||
| Silvio Baca | 162 | 748 | 2019 | ||
| Daniel Perales | 162 | 726 | 2019 | ||
| Stuart Hamilton | 162 | 716 | 2019 | ||
| Brian Barton | 162 | 643 | 2018 | ||
| Nick Swisher | 162 | 707 | 2017 | ||
| Mark Preusser | 162 | 678 | 2017 | ||
| Chris Snelling | 162 | 692 | 2016 | ||
| Juan Vazquez | 162 | 676 | 2016 | ||
| Hank Blalock | 162 | 665 | 2016 | ||
| Prince Gilbreath | 162 | 650 | 2016 | ||
| Miguel Almanzar | 162 | 636 | 2016 | ||
| Brandon Sing | 162 | 634 | 2016 | ||
| Robert Hatcher | 162 | 625 | 2016 | ||
| Juan Vazquez | 162 | 752 | 2015 | ||
| Robert Cervantes | 162 | 725 | 2015 | ||
| Juan Vazquez | 162 | 718 | 2014 | ||
| Lance Niekro | 162 | 690 | 2014 | ||
| Ken Harvey | 162 | 663 | 2014 | ||
| Jarrod Saltalamacchia | 162 | 654 | 2014 | ||
| Luis Rivas | 162 | 620 | 2014 | ||
| Adam Dunn | 162 | 684 | 2013 | ||
| Andy Phillips | 162 | 677 | 2013 | ||
| Jorge Padilla | 162 | 650 | 2013 | ||
| Jose Castillo | 162 | 587 | 2013 | ||
| Carlos Quentin | 162 | 713 | 2012 | ||
| Casey Rogowski | 162 | 635 | 2012 | ||
| Michael Clark | 162 | 627 | 2012 | ||
| Tommy Whiteman | 162 | 613 | 2012 | ||
| Michael Barrett | 162 | 673 | 2011 | ||
| Rontrez Johnson | 162 | 619 | 2011 | ||
| Endy Chavez | 162 | 739 | 2010 | ||
| Bobby Kielty | 162 | 704 | 2007 | ||
| Rafael Furcal | 162 | 701 | 2007 | ||
| Andruw Jones * | 162 | 681 | 2007 | ||
| Jose Cruz Jr. | 162 | 642 | 2007 | ||
| Mike Caruso | 162 | 633 | 2007 | ||
| Rob Mackowiak | 162 | 631 | 2007 | ||
| 41. | Alfonso Fraile | 161 | 677 | 2019 | |
| Mark Preusser | 161 | 717 | 2018 | ||
| Roger Bernadina | 161 | 652 | 2018 | ||
| Alfonso Romero | 161 | 649 | 2018 | ||
| Samuel Gladstone | 161 | 682 | 2017 | ||
| Keith Pollock | 161 | 663 | 2016 | ||
| Gabriel Crow | 161 | 701 | 2015 | ||
| Adam Jones | 161 | 608 | 2015 | ||
| Jorge Padilla | 161 | 721 | 2014 | ||
| Gabriel Crow | 161 | 656 | 2013 | ||
| Ben Francisco | 161 | 654 | 2013 | ||
| Samuel Gladstone | 161 | 652 | 2012 | ||
| Aaron Baldiris | 161 | 741 | 2009 | ||
| William Lamberth | 161 | 702 | 2009 | ||
| Jorge Cortes | 161 | 680 | 2009 | ||
| Jack Wilson | 161 | 634 | 2009 | ||
| Jack Wilson | 161 | 723 | 2008 | ||
| Matt Murton | 161 | 704 | 2008 | ||
| Jose Cruz Jr. | 161 | 679 | 2008 | ||
| Prince Gilbreath | 161 | 663 | 2008 | ||
| Ichiro Suzuki | 161 | 690 | 2007 | ||
| 62. | Richard Freeze | 160 | 737 | 2021 | |
| Lucas Garcia | 160 | 718 | 2021 | ||
| Jesus Gonzalez | 160 | 667 | 2019 | ||
| Barney Cobas | 160 | 747 | 2018 | ||
| Chad Gumbs | 160 | 683 | 2018 | ||
| Dave Alard | 160 | 662 | 2018 | ||
| Dylan Lammond | 160 | 653 | 2018 | ||
| Jonathan Lafreniere | 160 | 639 | 2018 | ||
| Carlo Barrera | 160 | 593 | 2018 | ||
| Everett Stadler | 160 | 678 | 2016 | ||
| Paul McAnulty | 160 | 658 | 2016 | ||
| Leopoldo Arguello | 160 | 634 | 2015 | ||
| Jeremy Hermida | 160 | 715 | 2014 | ||
| Merlin Justice | 160 | 639 | 2014 | ||
| Merlin Justice | 160 | 671 | 2013 | ||
| Frank Kirkman | 160 | 623 | 2013 | ||
| Travis Ishikawa | 160 | 674 | 2012 | ||
| Robert Cervantes | 160 | 642 | 2012 | ||
| Nick Green | 160 | 697 | 2009 | ||
| Lyle Overbay | 160 | 669 | 2007 | ||
| 82. | Connor Maccause | 159 | 697 | 2021 | |
| Hollis Defazio | 159 | 683 | 2021 | ||
| Felix Veach | 159 | 656 | 2021 | ||
| William Square | 159 | 651 | 2021 | ||
| Eladio Santacruz | 159 | 679 | 2020 | ||
| Paul Prosperie | 159 | 625 | 2020 | ||
| Juan Gonzalez | 159 | 691 | 2019 | ||
| Matt Moses | 159 | 674 | 2019 | ||
| Rueben Manzo | 159 | 673 | 2019 | ||
| Hollis Defazio | 159 | 670 | 2019 | ||
| Colby Springer | 159 | 644 | 2019 | ||
| Chris Snelling | 159 | 649 | 2018 | ||
| Lucas Garcia | 159 | 641 | 2018 | ||
| William Alcorn | 159 | 635 | 2018 | ||
| Johnnie Harley | 159 | 615 | 2018 | ||
| Kyle Walker | 159 | 662 | 2017 | ||
| Blair Thomson | 159 | 649 | 2017 | ||
| Michael Garciaparra | 159 | 644 | 2017 | ||
| Lee Tacker | 159 | 694 | 2016 |
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